In Ethiopia, cutaneous leishmaniasis (CL) is caused by Leishmania (L.) aethiopica and presents as a spectrum of clinical forms ranging from self-healing to persistent, disfiguring lesions. Monocytes are some of the first cells to encounter Leishmania …
Patients co-infected with visceral leishmaniasis (VL) and HIV-1 (VL/HIV patients) suffer from recurrent VL relapses and increased mortality. The aim of our study was to test the hypothesis that HIV patients who present with their first episode of VL …
The implementation of prospective drug resistance (DR) studies in the R&D pipelines is a common practice for many infectious diseases, but not for Neglected Tropical Diseases. Here, we explored and demonstrated the importance of this approach, using …
Background: Guinea worm (Dracunculus medinensis) was detected in Chad in 2010 after a supposed ten year absence, posing a challenge to the global eradication effort. Initiation of a village-based surveillance system in 2012 revealed a substantial …