Leishmaniasis in Ethiopia

Working with some excellent Ethiopian collaborators and in particular Pascale Kropf at Imperial college, London, we are using parasite genetics and RNA-seq of clinical samples to understand the pathogenesis and epidemiology of leishmaniasis in Ethiopia. Ethiopia is a uniquely interesting place for Leishmania research where a unique form of cutaneous leishmanaisis (CL), caused by L. aethiopica co-exists close to foci of VL due to two different genotypes of L. dononvani, which are separated by the East African rift valley. We have three on-going projects funded my the MRC and by a Wellcome fellowship awarded to Yegnasew Takele to work with Pascale.

James Cotton
James Cotton
Senior Staff Scientist

My research interests are in the genomics, and particularly population genomics of parasites, particularly those that cause neglected tropical diseases